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Breastfeeding Protects Against Allergic Asthma 2-29-08
Breastfeeding has proven to provide many benefits for babies and now protection
from allergic asthma can be added to that list of benefits. A study found that
airborne allergen is able to pass from mother to child through breast milk,
which creates a tolerance to the allergen.
The study investigated whether exposing lactating mice to the airborne allergen
ovalbumin, affected asthma development in the offspring. They found that
ovalbumin was efficiently transferred from the mother to the neonate through the
milk, leading to the development of immunological tolerance. Tolerance induction
relied on the presence of transforming growth factor–beta and was mediated by
regulatory CD4+ T lymphocytes, but did not require the transfer of
immunoglobulins through the milk.
Allergic asthma affects 300 million people worldwide and is characterized by
obstruction of the respiratory pathways in response to allergen exposure. Its
prevalence has increased in recent decades, probably due to changes in
environmental factors. Exposure to environmental antigens during infancy reduces
the likelihood of developing asthma. The finding in this study may pave the way
for the design of new strategies to prevent the development of allergic
diseases.
Source: Nature Medicine
Comment: Is the ever- increasing prevalence of asthma and allergies due to the decline in breastfeeding? I wonder?