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$2,000 For Exposure to Malaria 3-7-08

Seattle volunteers will be paid an estimated $2,000 or more to hold a paper cup containing mosquitoes infected with malaria against their arm, waiting for the insects to bite to test the effectiveness of new malaria vaccines.
The Seattle Biomedical Research Institute is collaborating with the PATH Malaria Vaccine Initiative to accelerate malaria vaccine research by opening a new vaccine-testing center in Seattle’s south Lake Union neighborhood. Scientists at the center will use early testing of vaccines to weed out those that don’t work so they can speed up research on the ones that are effective.
Malaria, which is spread by mosquitoes, kills more than a million people each year, most of them children. Deaths doubled in Africa over the past 20 years due to resistance to existing drugs and insecticides.
If the volunteers become infected with malaria symptoms usually develop within nine to 11 days, and they will be treated for malaria when the first parasites show up in their blood. The treatments last three days.
Testing subjects will get no sicker than someone with the flu and most won’t even miss a day of work after being exposed to malaria and then treated, said Dr. Patrick Duffy, head of the Seattle Biomedical Research Institute’s malaria research programs. They will need to stay in a downtown hotel for a few days and get daily medical tests, but can leave their room during the day because treatment for the virus would begin before it becomes contagious.