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AAAAI: A Mouse in the House Raises Asthma Risk 3-16-08

PHILADELPHIA, March 16 -- Mouse allergen at levels that may contribute to asthma is present in more than a third of American homes, researchers said here.

In households with concentration of mouse allergen greater than 1.6 mcg per gram of dust, rates of asthma in at least one household member were nearly 50% greater than in homes with lower mouse allergen levels, according to Päivi M. Salo, Ph.D., of the National Institute of Environmental Health Science in Research Triangle Park, N.C., and colleagues.

In 35% of homes, levels exceeded 1.6 mcg/g of dust. That level has been found in earlier research to be associated with increased rates of mouse allergen sensitization.

"It is advisable to get rid of mice in homes where allergic and asthmatic individuals reside," Dr. Salo said at the American Academy of Allergy, Asthma and Immunology meeting here.

The findings were part of an NIEHS-funded study of allergens and lead in 831 housing units scattered across the United States. The sample was intended to be representative of American homes and included a variety of home types, ages, and neighborhoods.

Dr. Salo said the survey found detectable levels of mouse allergen (primarily urine residue) in more than 82% of homes.

Dr. Salo reported that 8.9% of homes with mouse allergen levels above 1.6 mcg/g had a currently asthmatic household member, whereas current asthma prevalence in homes with mouse allergen levels at or below the threshold was 6.0% (P=0.05).

After adjusting for age, gender, race, smoking status, and season, the odds ratio for current asthma in homes with high levels of mouse allergen was 1.40 (95% CI 0.94 to 2.10).

The correlation was stronger in households where members were known to have allergies. There, the adjusted odds ratio for current asthma in homes with high mouse allergen levels was 1.93 (95% CI 1.14 to 3.27) while the effect was not seen in non-atopics (adjusted OR= 0.69, 95% CI: 0.33-1.44).

Rates of doctor-diagnosed asthma without recent symptoms, allergies, and hay fever did not differ significantly by mouse allergen level, nor did rates of wheezing.

Dr. Salo said apartments in high-rise buildings, mobile homes, older housing, and buildings in low-income neighborhoods were more likely than other homes to have high levels of mouse allergen.

She added that cats did not appear to be a solution to the mouse allergen problem. Findings from the NIEHS survey indicated that the presence of cats in households had little impact on levels of mouse allergens.

The data also indicated that, in households with atopic family members, the presence of the Fel D cat allergen along with high levels of mouse allergens doubled the risk of current asthma (OR 1.92, 95% CI 1.13 to 3.24)

What Can You Do?

Dr. Beth Dupree:

Get the mice out of the house! Do not use toxic mouse poisons or baits! There is to great a chance of second hand poisoning of pets or children. Plug up any holes or cranks in walls, floor boards, joists, around pipe entrances, cable or  telephone lines entering the home, furnace, or any other way in. Mice can squeeze through a 1/4 inch!

If you have a crawl space put mothballs (wear gloves and use 5 for every 1000 sq. ft) )under the house and in the attic. Mice hate peppermint essential oil; place it around any area you have seen mouse droppings. Clean all mouse droppings our of the house with Citrisolve and water. The droppings are a map for other mice. Keep all food, spices, mixes, etc; in the fridge, freezer or airtight containers and totes. Make sure pet food is keep completely in airtight containers. This is a major draw.

Go around the outside of the house and seal all cracks and holes. Once you have taken all these steps the Pest Offense plug in works great! I have used it in 4 houses and have never had pests.

Mice creep along walls. So make a spray of water and 40 drops peppermint essential oil. Spray this along every single wall edge, where it meets the floor, and every window, cabinets, etc..

This should get rid of your mouse problem without any dangerous chemicals!