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Men: Fight Osteoporosis By Increasing Vitamin C 10-9-08
Findings from a new study suggest
vitamin C
may be protective against bone loss in older men. Researchers funded by the
Agricultural Research Service (ARS) reported the findings in the October issue
of the Journal of Nutrition.
The study was led by epidemiologist Katherine Tucker with the Jean Mayer USDA
Human Nutrition Research Center on Aging (HNRCA) at Tufts University in Boston,
Mass. Tucker directs the HNRCA's Dietary Assessment and Epidemiology Research
Program.
Osteoporosis--a condition in which bones become porous and weak--affects about
10 million people in the U.S. population, and low bone mass is a public health
concern among another 44 million people aged 50 or older. The researchers wanted
to examine whether fruit- and vegetable-specific antioxidants such as
vitamin C
might decrease oxidative stress that is linked to accelerated bone loss.
In the Framingham Osteoporosis Study, bone mineral density at the hip, spine and
forearm was measured in 344 men and 540 women aged 75 on average.
Because people at risk for bone loss, such as smokers, may use
vitamin C
supplements more often, the potential effects of
vitamin C
intake obtained from diet, supplements, and both diet and supplements were
examined. Interactions based on smoking, calcium and vitamin E intakes were
tracked. The researchers observed significant positive associations for total
vitamin C--both
dietary and supplemental--among men who never smoked.
Among a subset of the participants--whose bone mineral density was again
measured after four years--different interactions were observed. During those
four years, total
vitamin C
appeared to be protective against losses in bone mineral density in two areas of
the hip among men with low calcium or vitamin E intakes. That finding is
consistent with previous reports by Tucker and other researchers that higher
fruit and vegetable intake has positive effects on bone mineral status.
The researchers did not observe significant effects of
vitamin C
intake on bone in women.