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Simulin from Fruits Protects People From Diabetic Effects of Dietary Sugars 11-07-08
by David Gutierrez
Researchers from ATM Metabolics say they have isolated a chemical, naturally
occurring in fruits and vegetables, that protects the body from the
diabetes-producing effects of sugars.
ATM Metabolics is a research company specializing in treatment of metabolic and
neurological disorders.
The researchers isolated and tested a chemical, which they call simulin, and
found that it accelerated the removal of excess sugar from the bloodstream,
increased the sensitivity of insulin receptors, reduced the amount of
carbohydrates absorbed, and reduced the amount of glucose manufactured by the
liver. It also helped "[mobilize] carbohydrates from the fat cells."
Calling simulin a "sugar defense mechanism," the researchers said their findings
suggested the chemical helps the body deal with sugar's potentially harmful
effects. If added to foods and beverages, they said, it might help protect
against diabetes and even allow diabetics to eat sugary foods again.
Simulin is not a sweetener, but rather a compound that could be added to already
sweetened products.
The researchers have speculated that the chemical evolved as a way to encourage
animals to eat more fruit by protecting them against diabetes.
"Fruit plants depend on their fruits being eaten to spread, so it makes sense
that they would do everything they could to keep their fruit on the menu," said
researcher Daryl Thompson. "This could be why humans didn't become diabetic
despite eating so much sugar in fruit and vegetables."
Thompson said that further studies of simulin's effects are underway to clear
the way for its use as a commercial food additive. He said that because the
product is natural, it should not need to receive special FDA approval, and
could probably achieve Generally Recognized As Safe status.
For the same reason, he expects companies and consumers to line up once the
product is ready.
"We've had a good response from the food industry," he said, "and we think
consumers will accept it because it is natural."